RNA Biochemistry / Structural Biology

​Robart  lab

publications

Chan RT, Peters JK, Robart AR, Wiryaman T, Rajashankar KR, Toor N. (2018) Structural basis for the second step of group II intron splicing. Nature Communications. 9(1).


Robart AR, Chan RT, Peters JK,  Rajashankar KR, Toor N. (2014) Crystal structure of a eukaryotic group II intron lariat. Nature. 514(7521):193-7.

Chan RT, Robart AR, Kanagalaghatta R, Pyle AM, Toor N. (2012) Crystal Structure of a Group II Intron in the Pre-Catalytic State. Nat Struct Mol Bio. 19(5):555-7.
 

Robart AR and Collins K (2011) Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation. Mol Cell. 42:308-18.

Robart AR and Collins K (2010) Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants. J Biol Chem. 285:4375-86.

Robart AR, O’Connor CM, Collins K (2010) Ciliate telomerase RNA loop IV nucleotides promote hierarchical RNP assembly and holoenzyme stability.  RNA. 16:563-71.

Robart AR, Seo W, Zimmerly S (2007) Insertion of group II intron retroelements after intrinsic transcriptional terminators. PNAS 104(16):6620-5

Toor N, Robart AR, Christianson J, Zimmerly S (2006) Self-splicing of a group IIC intron: 5’ exon recognition and alternative 5’ splicing events implicate the stem-loop motif of a transcriptional terminator. Nucleic Acids Res. 34(22):6461-71

Robart AR and Zimmerly S. (2005) Group II intron retroelements: function and diversity. Cytogenet Genome Res. 110 (1-4):589-97.

Robart AR, Montgomery NK, Smith KL, Zimmerly S. (2004). Principles of 3' splice site selection and alternative splicing for an unusual group II intron from Bacillus anthracis. RNA. 10:854-862.